Effect of Propionic Acid on Fatty Acid Oxidation and Ureagenesis

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Oxidation of propionic acid by Nocardia corallina.

Two pathways have been postulated for the conversion of propionic acid to pyruvic acid by liver mitochondria. Mahler and Huennekens (1953) suggested that propionic acid was oxidized to acrylic acid which was converted to pyruvic acid through Land D-lactic acids. The alternative pathway involves a direct carboxylation of propionic acid to succinic acid (Lardy and Adler, 1956; Flavin et al., 1955...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1976

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197607000-00010